NEWS

Source: Link Testing Instruments Co.,Ltd.

What is the reason for the ink layer to fall off on medicinal aluminum foil?

Quality problem: The ink layer on the aluminum foil surface of the pharmaceutical blister package has fallen off.

Cause analysis:

-Packaging material • The adhesion or heat resistance of the aluminum foil protective layer is poor-In addition to preventing the aluminum foil from oxidation and corrosion, the protective layer on the surface of the aluminum foil can also protect the printed layer on the surface of the aluminum foil from being scratched. If the adhesion or heat resistance of the protective layer is poor, when it falls off during heat sealing or other heating processes, the protective effect on the ink is weakened, so the ink layer is prone to being scratched and falling off. This can be verified by testing the adhesion and heat resistance of the protective layer.

• Improper control of the printing process-If the printing process is improper, it is easy to cause the adhesion and strength of the ink on the aluminum foil surface to decrease. After the protective layer is missing, the ink is prone to being scratched or falling off.

Expert advice:

-Pay attention to the monitoring of the adhesion and heat resistance of the protective layer of the medicinal aluminum foil.

-Appropriately adjust the printing process.

Typical quality cases:

--Test samples: Painkillers blister packaging (customers reported that the words printed on the aluminum foil surface of the blister packaging were easily scratched).

--Targeted test items: Adhesion of the protective layer, heat resistance of the protective layer.

--Test results: In the test of adhesion of the protective layer, the protective layer of the aluminum foil did not fall off, but in the test of heat resistance of the protective layer, the protective layer fell off significantly. Therefore, the heat resistance of the protective layer is poor. When it is heat-sealed or other high-temperature links, the protective layer is easy to fall off, which is the main reason why the printed words are easily scratched.

Heat Seal Tester LTH-H3

 

 

What properties should be focused on when pharmaceutical aluminum foil enters the factory?

(1) Barrier properties• Barrier properties to water vapor and oxygen in the environment - verified through water vapor permeability and oxygen permeability tests to prevent the poor barrier properties of the aluminum foil itself due to its own defects, which may cause the packaged drugs to be damp or oxidized during the shelf life.

(2) Physical and mechanical properties

• Heat sealing performance - verified through heat sealing strength test. If the heat sealing strength of the blister package is poor, the sealing effect of the drug is poor, resulting in gas easily entering the blister from the poor heat sealing point, causing deliquescence and oxidation of the drug. • Sealing performance - verified through sealing performance (negative pressure method) test, the parts of the finished product packaging that are prone to air leakage and leakage can be found.
• Adhesion strength of the protective layer - verified through the adhesion test of the protective layer to prevent the ink layer from being scratched, the protective layer from being stained with the adhesive layer, or the aluminum foil from being oxidized after the protective layer falls off.
• Heat resistance of protective layer - verified by heat resistance test of protective layer. If the heat resistance of protective layer is poor, it is easy to fall off in the heat-exposed process such as heat sealing process. Adhesive coating amount - verified by the difference of adhesive coating amount to prevent poor heat sealing strength caused by large difference of adhesive coating amount.
• Rolling performance - verified by unwinding performance test, mainly to test whether the adhesive layer and protective layer will be bonded together during unwinding. If the adhesive layer and protective layer are bonded together, it will affect the unwinding speed and thus the production efficiency. At the same time, no matter which layer is pulled off, it will have a certain impact on the quality of aluminum foil.
• Hygienic performance Volatile content - verified by volatile test to prevent the total volatile content from being too high and contaminating the medicine after packaging. 

Gas Permeability Tester GTC-203H

 

What are the key performance concerns of aluminum-plastic composite hoses?

(1) Barrier properties • Barrier properties to water vapor and oxygen - verified by water vapor permeability test and oxygen permeability test respectively, to prevent the packaged ointment from becoming hard and discolored due to poor barrier properties of the hose.

(2) Physical and mechanical properties • Pressure resistance - verified by pressure resistance test to prevent leakage and rupture of finished ointment packaging due to compression during transportation and storage. • Composite fastness - verified by inner layer and sub-inner layer peel strength test. If the peel strength is low, stratification is likely to occur after filling the ointment or when it is squeezed.

• Heat sealing effect - verified by tube body heat seal strength test and tube tail heat seal strength test to prevent leakage at the heat seal part due to low heat seal strength.
• Sealing performance - verified by sealing test to prevent leakage due to poor fit between the tube body and the tube cap.

(3) Hygienic performance • Solvent residue - verified by the solvent residue test. If there is a large amount of residual organic solvent in the aluminum-plastic composite hose, it is easy to migrate into the ointment during contact with the ointment, causing contamination.

Automatic Tensile Tester XLW-500N

 

For more details please visit www.linktesting.org